摘要

在这项研究中，研究了泰乐菌素发酵渣（TFDs）和不同添加浓度铜（Cu）的污泥的好氧共堆肥，以检测抗生素抗性基因（ARG），金属抗性基因（MRG）和流动基因 元素（MGE）。 结果表明，两种浓度的铜不仅影响非生物因子，而且影响抗性基因的相对丰度。 高浓度的Cu抑制微生物群落的代谢能力和固氮过程，而对TYL和TOC的降解影响不大。 ermT，mefA，mphA的丰度增加部分归因于毒性效应和由MRG反映的重金属的选择性压力。 pH值，生物铜，有机物和ARG等环境因子之间存在显着相关性。

In this study, aerobic co-composting of tylosin fermentation dregs (TFDs) and sewage sludge with different adding concentrations of copper (Cu) was investigated to inspect the fate of antibiotic resistance genes (ARGs), metal resistance genes (MRGs) and mobile genetic elements (MGEs). Results showed that two concentrations of Cu did affect not only the abiotic factors but the relative abundances of resistance genes. High concentration of Cu inhibited the metabolic capacity of microbial community and the nitrogen-fixing process while had little effect on the degradation of TYL and TOC. The abundance ofermT, mefA, mphA increased partly attributed to the toxic effects and co-selective pressure from heavy metal reflected by MRGs. There was significant correlation among some environmental factors like pH, bio-Cu, organic matters and ARGs.

https://www.sciencedirect.com/science/article/pii/S0960852417321867