摘要
      由于抗生素的广泛使用，抗生素抗性基因（ARGs）存在于水环境中，并在水柱和沉积物之间迁移。本文基于土柱实验，研究了ARGs在水沙界面的垂直传输机制。旨在揭示物理化学因素（盐度和pH）对四种ARG（sul（I）、tet（A）、tet（X）、te特（M）和I类整合素（intI1））在水-沉积物界面迁移的影响。研究发现，盐度和pH值都会影响ARGs在沉积物和水中的迁移。盐度削弱了sul（I）、tet（A）和tet（X）的垂直迁移，而盐度对tet（M）的影响相反。sul（I）、tet（A）、intI1和16s的垂直迁移在酸性条件（pH=4）下减少，而在碱性条件（pH=9.18）下增强。对于tet（X）和tet（M），酸性条件（pH=4）和碱性条件（pH=8.18）都削弱了垂直迁移。
ABSTRACT
Due to the widespread utilization of antibiotics, antibiotic resistance genes (ARGs) are found to be existing in water environment, and migrate between the water column and sediments. Based on soil column experiments, the vertical transport mechanism of ARGs at water-sediment interface was studied in this paper. It aims to reveal the effects of physicochemical factors (salinity and pH) on the migration of four ARGs: sul(I), tet(A), tet(X), tet(M) and Class I integron (intI1) at water-sediment interface. It was found that salinity and pH both can affect the migration of ARGs between sediment and water. Salinity weakened the vertical migrations of sul(I), and tet(A), and tet(X), while the effect of salinity on tet(M) was opposite. The vertical migrations of sul(I), tet(A), intI1 and 16s were decreased under the acidic conditions (pH=4), while they were enhanced under the alkaline conditions (pH=9.18). For tet(X) and tet(M), both of acidic conditions (pH=4) and alkaline conditions (pH=9.18) weakened the vertical migration.

https://onepetro.org/ISOPEIOPEC/proceedings-abstract/ISOPE22/All-ISOPE22/ISOPE-I-22-201/493820