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中国饮用水耐药性动态分析

发布者:抗性基因网 时间:2023-06-08 浏览量:249

摘要
      抗生素耐药性(AR)是当今时代一种严重的环境危害。抗生素抗性基因(ARGs)是在环境中传播AR的基本实体。ARGs很可能从非致病性微生物转移到致病性微生物,这些微生物可能最终导致人类和其他生物的AR。饮用水(DW)是ARGs与人类之间的主要相互作用途径。作为抗生素的最高生产国和消费国,中国对发展超级细菌和ARGs的传播构成了潜在威胁。在此,我们试图全面审查来自中国主要DW来源的ARG。此外,还评估了ARGs对中国DW的起源和影响因素。常用的方法,包括古典方法和现代方法,正在进行汇编。此外,还概述了DW ARG在中国带来的风险和缓解策略。总的来说,我们相信这项审查将有助于评估中国DW中的ARGs及其对人类和其他动物的传播,并最终帮助该领域的政策制定者和科学家在紧急情况下应对这一问题。
Abstract
Antibiotic resistance (AR) is a serious environmental hazard of the current age. Antibiotic resistance genes (ARGs) are the fundamental entities that spread AR in the environment. ARGs are likely to be transferred from the non-pathogenic to pathogenic microbes that might ultimately be responsible for the AR in humans and other organisms. Drinking water (DW) is the primary interaction route between ARGs and humans. Being the highest producer and consumer of antibiotics China poses a potential threat to developing superbugs and ARGs dissemination. Herein, we comprehensively seek to review the ARGs from dominant DW sources in China. Furthermore, the origin and influencing factors of the ARGs to the DW in China have been evaluated. Commonly used methods, both classical and modern, are being compiled. In addition, the risk posed and mitigation strategies of DW ARGs in China have been outlined. Overall, we believe this review would contribute to the assessment of ARGs in DW of China and their dissemination to humans and other animals and ultimately help the policymakers and scientists in the field to counteract this problem on an emergency basis.

https://www.sciencedirect.com/science/article/abs/pii/S0269749123001872