摘要
      抗生素耐药性病原体的感染大多发生在农村地区。本文研究了抗生素抗性基因（ARGs）通过粪便污水处理设施向典型农村地区生态系统的传播。考虑了家用三室化粪池（TC）、家用沼气池（BD）、污水处理厂（WWTP）、菜地、水塘等。BDs和WWTP可使粪便污水中ARGs的相对丰度分别降低80%和60%。而TC对ARG没有还原能力。快速期望最大化微生物源跟踪（FEAST）分析显示，TC和BD对农村地区地表水体（水塘）的ARGs贡献了相当大的比例（15-22%）。大多数ARG倾向于在水体沉积物中沉淀，并停止向下游移动。同时，微生物的迁移比ARGs的迁移更活跃。研究结果为农村粪便污水的管理和ARGs的控制提供了科学的基础数据。
Abstract
Infection of antibiotic-resistant pathogens mostly occurs in rural areas. In this paper, the dissemination of antibiotic resistance genes (ARGs) through fecal sewage treatment facilities to the ecosystem in a typical rural area is investigated. Household three-chamber septic tanks (TCs), household biogas digesters (BDs), wastewater treatment plants (WWTPs), vegetable plots, water ponds, etc. Are taken into account. The relative abundance of ARGs in fecal sewage can be reduced by BDs and WWTPs by 80% and 60%, respectively. While TCs show no reduction ability for ARGs. Fast expectation-maximization microbial source tracking (FEAST) analysis revealed that TCs and BDs contribute a considerable percentage (15–22%) of ARGs to the surface water bodies (water ponds) in the rural area. Most ARGs tend to precipitate in the sediments of water bodies and stop moving downstream. Meanwhile, the immigration of microorganisms is more active than that of ARGs. The results provide scientific basic data for the management of fecal sewage and the controlling of ARGs in rural areas.

https://www.sciencedirect.com/science/article/abs/pii/S030147972300227X