摘要
      近年来，抗生素耐药性基因的广泛传播给饮用水的生物安全带来了巨大的风险。随着人们对饮用水质量的需求不断增加，ARGs被认为是一种新的污染物，可能会导致严重的公共卫生问题。大量研究表明，饮用水处理厂的消毒过程可以去除ARGs。然而，传统消毒方法对ARGs的影响有其自身的缺点。茶多酚作为一种绿色、高效、无消毒的副产品消毒剂，越来越受到研究人员的关注。通过宏基因组测序分析了臭氧-茶多酚消毒工艺对自来水厂过滤出水中ARGs的影响。结果表明，臭氧-茶多酚消毒工艺适用于含有较多四环素、磺酰胺、β-内酰胺和氨基糖苷类抗性基因的特定原水，水中总抗性基因的去除率高于传统消毒工艺。臭氧-茶多酚消毒过程对ARGs的影响是通过破坏ARGs分子和抑制ARGs宿主细胞的增殖来减少ARGs转移。茶多酚作为一种辅助消毒剂，对传统消毒过程中去除ARGs的能力具有重要意义。
Abstract
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In recent years, the wide spread of antibiotic resistance genes (ARGs) has brought tremendous risk to the biological safety of drinking water. With the increasing demand for drinking water quality, ARGs have been regarded as a new pollutant that may cause serious public health problems. A large number of studies have shown that the disinfection process of drinking water treatment plants can remove ARGs. However, the effects of traditional disinfection methods on ARGs have their own disadvantages. Tea polyphenols have attracted more and more researchers’ attention as a green, efficient and non-disinfection by-products disinfectant. The effect of the ozone–tea polyphenols disinfection process on ARGs in filtered effluent of waterworks was analyzed by using metagenomic sequencing. The result shows that the ozone–tea polyphenols disinfection process is suitable for specific raw water containing more tetracycline, sulfonamide, β-lactam, and aminoglycoside resistance genes, and the removal rate of total resistance genes in water is higher than the traditional disinfection process. The effect of the ozone–tea polyphenols disinfection process on ARGs is to reduce the transfer of ARGs by destroying ARGs molecules and inhibiting the proliferation of ARGs host cells. As an assistant disinfectant, tea polyphenols have significance for the ability to remove ARGs during traditional disinfection.

https://iwaponline.com/aqua/article/71/4/507/87768/Effect-of-ozone-tea-polyphenols-as-a-drinking