摘要
从季节和空间两个方面研究了中国长江口附近海域沉积物中典型抗生素抗性基因的污染特征。所有采样点沉积物中磺胺类药物sul1、sul2、四环素tetW和喹诺酮类药物gyrA抗性基因的阳性率均为100%，表明长江口附近海域受到这些ARG的广泛污染。sul1在大多数采样点占据优势，是长江口附近海域沉积物中的主要抗性基因。从季节变化特征来看，汛期ARGs的绝对丰度高于旱季。从空间分布特征来看，南方站点的ARGs绝对丰度大多高于北方站点，高丰度站点大多位于海岸附近。不同的ARG也表现出不同的空间分布特征。揭示长江口附近海域沉积物中典型ARGs的污染特征，可以为保护该地区和长江流域的环境提供有价值的信息。
Abstract
The pollution characteristics of the typical antibiotic resistance genes (ARGs) in the sediments of the sea area adjacent to the Yangtze Estuary, China were investigated with both seasonal and spatial insights. The positive rates of sulfonamides sul1, sul2, tetracycline tetW and quinolone gyrA resistance genes in the sediments of all sampling sites were 100%, indicating that the sea area adjacent to the Yangtze Estuary were extensively polluted by these ARGs. Occupying a dominance in most sampling sites, sul1 was found to be the dominant resistance gene in the sediments of the sea area adjacent to the Yangtze Estuary. In terms of seasonal variation characteristics, the absolute abundances of the ARGs in flood season were higher than those in dry season. In terms of spatial distribution characteristics, the absolute abundances of the ARGs in the southern sites were mostly higher than those in the northern sites, and the high abundance sites were mostly located near the coast. Different ARGs also showed different spatial distribution characteristics. The disclosure of the pollution characteristics of the typical ARGs in the sediments of the sea area adjacent to the Yangtze Estuary can provide valued information for protecting the environment of this area as well as the Yangtze River Basin.

https://www.sciencedirect.com/science/article/pii/S0269749122016840