摘要
      污水污泥是污水处理厂中抗生素、抗生素抗性基因（ARGs）和抗生素抗性细菌（ARB）的重要宿主，污水污泥的回收利用可能威胁人类健康和环境安全。污泥处理和处置有望控制这些风险，本综述总结了抗生素、ARGs和ARB在污泥中的命运和控制效率，这些污泥涉及不同的过程，即崩解、厌氧消化、好氧堆肥、干燥、热解、人工湿地和土地应用。此外，还综述了复杂污泥中抗生素、ARGs和ARB的分析和表征方法，并对土地利用中涉及的定量风险评估方法进行了全面讨论。这篇综述有利于污泥处理和处置过程的优化，包括污泥中抗生素、ARGs和ARB的环境风险控制。此外，还提出了目前研究的局限性和差距，例如污泥改良土壤中抗生素耐药性风险评估，以推进未来的研究。
Abstract
Sewage sludge is an important reservoir of antibiotics, antibiotic resistance genes (ARGs), and antibiotic resistant bacteria (ARB) in wastewater treatment plants (WWTPs), and the reclamation of sewage sludge potentially threats human health and environmental safety. Sludge treatment and disposal are expected to control these risks, and this review summarizes the fate and controlling efficiency of antibiotics, ARGs, and ARB in sludge involved in different processes, i.e., disintegration, anaerobic digestion, aerobic composting, drying, pyrolysis, constructed wetland, and land application. Additionally, the analysis and characterization methods of antibiotics, ARGs, and ARB in complicate sludge are reviewed, and the quantitative risk assessment approaches involved in land application are comprehensively discussed. This review benefits process optimization of sludge treatment and disposal, with regard to environmental risks control of antibiotics, ARGs, and ARB in sludge. Furthermore, current research limitations and gaps, e.g., the antibiotic resistance risk assessment in sludge-amended soil, are proposed to advance the future studies.

https://www.sciencedirect.com/science/article/abs/pii/S0048969723013888